ResultsĪ total of 127 patients were enrolled, and there were 111 deaths (87.4%) within the 7-year observational period. We retrospectively reviewed the medical records of first-diagnosed patients with advanced PC who were admitted to Konkuk University Medical Center from 2005 to 2011. This study aimed to evaluate the impact of hemoglobin A1c (HbA1c) levels on PC survival. Although DM and hyperglycemia are considered risk factors for pancreatic cancer (PC), antidiabetic treatments for patients with advanced PC have been overlooked. Pre-existing diabetes mellitus (DM) has been identified as an adverse prognostic variable associated with increased mortality in various cancers. The editor retains the right to determine publication priorities, the style of the paper, and to request, if necessary, that the material submitted be shortened for publication. In many cases, papers may be rejected despite favorable reviews because of editorial policy or a lack of space. The final responsibility for the decision to accept or reject lies with the editors. We reserve the right to return manuscripts in which no reviewers are suggested. We may not always use the reviewers you recommend, but suggesting reviewers will make our reviewer database much richer in the end, everyone will benefit. It would be very helpful if you could suggest a selection of reviewers and include their contact details. The remaining articles are usually sent to two reviewers. A decision about these papers will usually be made within two or three weeks. Tell your healthcare provider right away if you get symptoms of gallbladder problems, which may include pain in your upper stomach (abdomen), fever, yellowing of skin or eyes (jaundice), and clay-colored stools.All papers submitted to Gut and Liver are reviewed by the editorial team before being sent out for an external peer review to rule out papers that have low priority, insufficient originality, scientific flaws, or the absence of a message of importance to the readers of the Journal. Gallbladder problems have happened in some people who use Mounjaro. Tell your healthcare provider if you have changes in vision during treatment with Mounjaro. Tell your healthcare provider if you have stomach problems that are severe or will not go away.Ĭhanges in vision. Stomach problems, sometimes severe, have been reported in people who use Mounjaro. It is important for you to drink fluids to help reduce your chance of dehydration. In people who have kidney problems, diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration), which may cause kidney problems to get worse. Stop using Mounjaro and get medical help right away if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue or throat, problems breathing or swallowing, severe rash or itching, fainting or feeling dizzy, and very rapid heartbeat. Signs and symptoms of low blood sugar may include dizziness or light-headedness, sweating, confusion or drowsiness, headache, blurred vision, slurred speech, shakiness, fast heartbeat, anxiety, irritability, or mood changes, hunger, weakness and feeling jittery. Your risk for getting low blood sugar may be higher if you use Mounjaro with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin. You may feel the pain from your abdomen to your back. Stop using Mounjaro and call your healthcare provider right away if you have severe pain in your stomach area (abdomen) that will not go away, with or without vomiting. Inflammation of the pancreas (pancreatitis). Mounjaro may cause serious side effects, including: If you have any of these symptoms, tell your healthcare provider.ĭo not use Mounjaro if you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC).ĭo not use Mounjaro if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).ĭo not use Mounjaro if you are allergic to it or any of the ingredients in Mounjaro. Watch for possible symptoms, such as a lump or swelling in the neck, hoarseness, trouble swallowing, or shortness of breath. Mounjaro may cause tumors in the thyroid, including thyroid cancer.
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